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KMID : 1009020230210040665
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Clinical Psychopharmacology and Neuroscience
2023 Volume.21 No. 4 p.665 ~ p.675
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Brain Neuroplasticity after Treatment with Antiseizure: A Review
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Debora Lopes Silva de Souza
Hosana Mirelle Goes e Silva Costa
Francisca Idalina Neta
Paulo Leonardo Araujo de Gois Morais
Luis Marcos de Medeiros Guerra
Fausto Pierdona Guzen
Lucidio Clebeson de Oliveira
Jose Rodolfo Lopes de Paiva Cavalcanti
Lee Ki-Jong
Claudio Lopes de Vasconcelos
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Abstract
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Epilepsy is a disease characterized by the periodic occurrence of seizures. Seizures can be controlled by antiseizure medications, which can improve the lives of individuals with epilepsy when given proper treatment. Therefore, this study aimed to review the scientific literature on brain neuroplasticity after treatment with antiseizure drugs in different regions of the brain. According to the findings, that several antiseizure, such as lamotrigine, diazepam, levetiracetam, and valproic acid, in addition to controlling seizures, can also act on neuroplasticity in different brain regions. The study of this topic becomes important, as it will help to understand the neuroplastic mechanisms of these drugs, in addition to helping to improve the effectiveness of these drugs in controlling the disease.
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KEYWORD
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Neuroplasticity, Neuronal plasticity, Anticonvulsant drugs, Antiepileptic, Seizures, Epilepsy
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